Summary of Job Purpose and Principal Duties
We are seeking a postdoctoral researcher to participate in a collaborative project between the Division of Signal Transduction Therapy (DSTT) and one of the world’s major pharmaceutical companies.
The number and activation state of intra-tumoral DCs critically define the anti-tumour immune response. Importantly, cytokines have a profound effect on the mobilization and generation of functionally mature and highly cross-presenting DCs. The aim of the project is to engineer cytokines with unprecedented DC-activation potential.
For informal enquiries please contact Dr Ignacio Moraga firstname.lastname@example.org
Summary of Skills, Experience and Qualifications
PhD with outstanding academic track record and at least one first authored publication in an internationally recognised peer-reviewed journal.
Strong background in Immunology, Molecular Biology and Signal Transduction would be preferable.
Experience and strong interest in signal transduction research and how disruptions of these pathways are linked to human disease.
Capable of working in a team, but able to plan and work independently.
Excellent communication skills and knowledge of the English language are essential.
The candidate should have ambitions to become a successful independent researcher either in academia or the pharmaceutical/biotechnology industry.
Appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. The initial appointment would be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 25 - 28 £29,176 - £31,866).
College / School / Directorate Information
School of Life Sciences:
School of Life Sciences at the University of Dundee is the highest-rated for Biological Sciences in the UK by the main standard of University research performance REF2014 (http://www.lifesci.dundee.ac.uk/). Comprising about 100 research groups, the highest number of citations-per-paper for biological sciences in Europe (2013 and 2014 QS World University Rankings), over £100 million of research income in 2013 and nearly 900 staff from over 60 countries worldwide, the School enjoys a reputation as one of the most dynamic international centres for molecular cell biology, with outstanding laboratory and technology facilities. 'Lateral' and 'vertical' interactions within and between research groups are actively encouraged and 13% of publications in the past 5 years have been collaborations between two or more groups.
Division of Signal Transduction Unit:
The Division of Signal Transduction Therapy (DSTT) was established in 1998. This division operates as a unique collaboration between scientists in the MRC-PPU (all PIs including Ronald Hay FRS Honorary PI of MRC-PPU) and signalling researchers at the University of Dundee’s School of Life Sciences (Ignacio Moraga, Simon Arthur, Doreen Cantrell FRS, Alessio Ciulli, Paul Crocker, Grahame Hardie FRS and Carol MacKintosh) and three leading pharmaceutical companies (Boehringer Ingelheim, GlaxoSmithKline, Merck Serono). The DSTT is widely regarded as a model for how academia should interact with industry, The DSTT operates as a simple bridging mechanism to enable our PIs working on ubiquitylation and phosphorylation to effectively interact with three major pharmaceutical companies to help accelerate the early stages of drug discovery. The DSTT model enables industrial researchers working in any of the worldwide outlets of three pharmaceutical companies to effectively work with the ~200 Dundee-based researchers that participate in the collaboration to understand the fundamentals of the molecular causes of disease that result from disruptions in protein phosphorylation and ubiquitylation networks.
The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.